{"id":100,"date":"2026-02-01T09:53:17","date_gmt":"2026-02-01T01:53:17","guid":{"rendered":"https:\/\/lovejade.org\/?p=100"},"modified":"2026-02-01T09:53:18","modified_gmt":"2026-02-01T01:53:18","slug":"%e5%b7%b4%e9%87%91%e6%a3%ae%e6%b0%8f%e7%97%87%e8%88%87%e9%9d%92%e5%85%89%e7%9c%bc%e7%9a%84%e9%97%9c%e4%bf%82","status":"publish","type":"post","link":"https:\/\/lovejade.org\/?p=100","title":{"rendered":"\u5df4\u91d1\u68ee\u6c0f\u75c7\u8207\u9752\u5149\u773c\u7684\u95dc\u4fc2"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The relationship between Parkinson&#8217;s disease and glaucoma<\/p>\n\n\n\n<div class=\"wp-block-uagb-tabs uagb-block-dd443de9 uagb-tabs__wrap uagb-tabs__hstyle1-desktop uagb-tabs__vstyle6-tablet uagb-tabs__stack1-mobile\" data-tab-active=\"0\"><ul class=\"uagb-tabs__panel uagb-tabs__align-left\" role=\"tablist\"><li class=\"uagb-tab uagb-tabs__active\" role=\"none\"><a href=\"#uagb-tabs__tab0\" class=\"uagb-tabs-list uagb-tabs__icon-position-left\" data-tab=\"0\" role=\"tab\"><div>\u4e2d\u6587<\/div><\/a><\/li><li class=\"uagb-tab \" role=\"none\"><a href=\"#uagb-tabs__tab1\" class=\"uagb-tabs-list uagb-tabs__icon-position-left\" data-tab=\"1\" role=\"tab\"><div>English<\/div><\/a><\/li><\/ul><div class=\"uagb-tabs__body-wrap\">\n<div class=\"wp-block-uagb-tabs-child uagb-tabs__body-container uagb-inner-tab-0\" aria-labelledby=\"uagb-tabs__tab0\">\n<p class=\"wp-block-paragraph\">\u5df4\u91d1\u68ee\u6c0f\u75c7\uff08Parkinson&#8217;s Disease, PD\uff09\u8207\u9752\u5149\u773c\uff08Glaucoma\uff09\u770b\u4f3c\u662f\u5169\u500b\u622a\u7136\u4e0d\u540c\u7684\u75be\u75c5\u2014\u2014\u4e00\u500b\u95dc\u4e4e\u5927\u8166\u904b\u52d5\u63a7\u5236\uff0c\u4e00\u500b\u95dc\u4e4e\u8996\u529b\u640d\u5931\u2014\u2014\u4f46\u91ab\u5b78\u754c\u7814\u7a76\u767c\u73fe\uff0c\u9019\u5169\u8005\u4e4b\u9593\u5176\u5be6\u5b58\u5728\u8457\u6df1\u5c64\u7684<strong>\u795e\u7d93\u9000\u5316\u6027<\/strong>\u806f\u7e6b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7c21\u55ae\u4f86\u8aaa\uff0c\u5b83\u5011\u5c31\u50cf\u662f\u300c\u4f4f\u5728\u4e0d\u540c\u5668\u5b98\u7684\u89aa\u621a\u300d\uff0c\u5171\u4eab\u4e86\u67d0\u4e9b\u81f4\u75c5\u7684\u751f\u7269\u85cd\u5716\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">1. \u5171\u540c\u7684\u795e\u7d93\u9000\u5316\u672c\u8cea<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5df4\u91d1\u68ee\u6c0f\u75c7\u4e3b\u8981\u662f\u5927\u8166\u4e2d<strong>\u591a\u5df4\u80fa\u795e\u7d93\u5143<\/strong>\u7684\u6d41\u5931\uff0c\u800c\u9752\u5149\u773c\u5247\u662f\u8996\u7db2\u819c\u4e0a**\u8996\u7db2\u819c\u795e\u7d93\u7bc0\u7d30\u80de\uff08RGCs\uff09**\u7684\u51cb\u4ea1\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7d30\u80de\u51cb\u4ea1\u6a5f\u5236\uff1a<\/strong> \u5169\u8005\u90fd\u6d89\u53ca\u7c92\u7dda\u9ad4\u529f\u80fd\u969c\u7919\u3001\u6c27\u5316\u58d3\u529b\u4ee5\u53ca\u767c\u708e\u53cd\u61c9\u3002<\/li>\n\n\n\n<li><strong>\u86cb\u767d\u8cea\u7570\u5e38\uff1a<\/strong> \u7814\u7a76\u767c\u73fe\uff0c\u5728\u67d0\u4e9b\u9752\u5149\u773c\u60a3\u8005\u7684\u8996\u7db2\u819c\u4e2d\uff0c\u4e5f\u89c0\u5bdf\u5230\u4e86\u8207\u5df4\u91d1\u68ee\u6c0f\u75c7\u76f8\u95dc\u7684\u7570\u5e38\u86cb\u767d\u8cea\u6c89\u7a4d\uff08\u5982 $\\alpha$-\u7a81\u89f8\u6838\u86cb\u767d\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">2. \u300c\u591a\u5df4\u80fa\u300d\u7684\u95dc\u9375\u89d2\u8272<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u5011\u901a\u5e38\u8a8d\u70ba\u591a\u5df4\u80fa\u53ea\u8ddf\u5927\u8166\u7684\u5feb\u6a02\u6216\u904b\u52d5\u6709\u95dc\uff0c\u4f46\u5176\u5be6<strong>\u8996\u7db2\u819c\u5167\u4e5f\u542b\u6709\u591a\u5df4\u80fa\u795e\u7d93\u5143<\/strong>\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8996\u89ba\u8abf\u7bc0\uff1a<\/strong> \u8996\u7db2\u819c\u4e2d\u7684\u591a\u5df4\u80fa\u8ca0\u8cac\u8abf\u7bc0\u5c0d\u6bd4\u654f\u611f\u5ea6\u3001\u984f\u8272\u8fa8\u8b58\u53ca\u5149\u9069\u61c9\u3002<\/li>\n\n\n\n<li><strong>\u4ea4\u4e92\u5f71\u97ff\uff1a<\/strong> \u5df4\u91d1\u68ee\u6c0f\u75c7\u60a3\u8005\u56e0\u70ba\u5168\u8eab\u6027\u591a\u5df4\u80fa\u6c34\u5e73\u4e0b\u964d\uff0c\u5e38\u6703\u51fa\u73fe\u8996\u7db2\u819c\u8b8a\u8584\u7684\u73fe\u8c61\u3002\u9019\u7a2e\u8b8a\u8584\u7684\u8868\u73fe\u8207\u9752\u5149\u773c\u9020\u6210\u7684\u795e\u7d93\u53d7\u640d\u5728\u81e8\u5e8a\u5f71\u50cf\u4e0a\u975e\u5e38\u76f8\u4f3c\uff0c\u6709\u6642\u5bb9\u6613\u9020\u6210\u8aa4\u8a3a\u6216\u6f0f\u8a3a\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">3. \u85e5\u7269\u4f7f\u7528\u7684\u6f5b\u5728\u98a8\u96aa\uff08\u975e\u5e38\u91cd\u8981\uff09<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u5982\u679c\u60a8\u6216\u89aa\u53cb\u540c\u6642\u60a3\u6709\u9019\u5169\u7a2e\u75be\u75c5\uff0c\u5fc5\u9808\u7279\u5225\u6ce8\u610f\u5df4\u91d1\u68ee\u6c0f\u75c7\u7684\u85e5\u7269\u5c0d\u773c\u58d3\u7684\u5f71\u97ff\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6297\u81bd\u9e7c\u85e5\u7269\uff08Anticholinergics\uff09\uff1a<\/strong> \u5e38\u898b\u65bc\u6cbb\u7642\u5df4\u91d1\u68ee\u6c0f\u75c7\u7684\u9707\u986b\u3002\u9019\u985e\u85e5\u7269\u53ef\u80fd\u6703\u5c0e\u81f4\u6563\u77b3\uff0c\u9032\u800c\u5f15\u767c<strong>\u6025\u6027\u9589\u9396\u6027\u9752\u5149\u773c<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u5de6\u65cb\u591a\u5df4\uff08L-Dopa\uff09\uff1a<\/strong> \u96d6\u7136\u662f\u6cbb\u7642 PD \u7684\u9996\u9078\u85e5\u7269\uff0c\u4f46\u5728\u6975\u5c11\u6578\u60c5\u6cc1\u4e0b\u53ef\u80fd\u8207\u773c\u58d3\u6ce2\u52d5\u6709\u95dc\u3002<\/li>\n<\/ul>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>\u26a0\ufe0f \u6eab\u99a8\u63d0\u9192\uff1a<\/strong> \u82e5\u60a8\u6b63\u5728\u670d\u7528\u5df4\u91d1\u68ee\u6c0f\u75c7\u85e5\u7269\u4e14\u88ab\u8a3a\u65b7\u51fa\u6709\u300c\u7a84\u89d2\u578b\u9752\u5149\u773c\u300d\uff0c\u52d9\u5fc5\u4e3b\u52d5\u544a\u77e5\u795e\u7d93\u5167\u79d1\u8207\u773c\u79d1\u91ab\u5e2b\uff0c\u4ee5\u4fbf\u8abf\u6574\u7528\u85e5\u3002<\/p>\n<\/blockquote>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">4. \u81e8\u5e8a\u4e0a\u7684\u95dc\u806f\u6578\u64da<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u6839\u64da\u8fd1\u5e74\u7684\u5927\u6578\u64da\u8ffd\u8e64\u7814\u7a76\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5df4\u91d1\u68ee\u6c0f\u75c7\u60a3\u8005\u7f79\u60a3\u9752\u5149\u773c\u7684\u6a5f\u7387\uff0c\u901a\u5e38\u6bd4\u4e00\u822c\u540c\u9f61\u4eba\u7a0d\u9ad8\u3002<\/li>\n\n\n\n<li>\u540c\u6a23\u5730\uff0c\u67d0\u4e9b\u9752\u5149\u773c\u60a3\u8005\u5728\u672a\u4f86\u51fa\u73fe\u904b\u52d5\u969c\u7919\u6216\u767c\u5c55\u6210 PD \u7684\u98a8\u96aa\u4e5f\u7565\u6709\u63d0\u5347\u3002<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">\u9019\u986f\u793a\u4e86\u9019\u5169\u8005\u53ef\u80fd\u64c1\u6709\u5171\u540c\u7684\u57fa\u56e0\u6613\u611f\u6027\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">\u6211\u53ef\u4ee5\u5982\u4f55\u5354\u52a9\u60a8\uff1f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9019\u5169\u8005\u7684\u95dc\u4fc2\u975e\u5e38\u5fae\u5999\uff0c\u5982\u679c\u60a8\u662f\u5e6b\u9577\u8f29\u8a62\u554f\uff0c\u6216\u8005\u81ea\u5df1\u6709\u76f8\u95dc\u7591\u616e\uff0c<strong>\u60a8\u662f\u5426\u60f3\u4e86\u89e3\u5177\u9ad4\u7684\u300c\u7528\u85e5\u5b89\u5168\u6aa2\u67e5\u6e05\u55ae\u300d\uff0c\u6216\u662f\u60f3\u77e5\u9053\u5df4\u91d1\u68ee\u6c0f\u75c7\u60a3\u8005\u65e5\u5e38\u8a72\u5982\u4f55\u9032\u884c\u773c\u90e8\u8b77\u7406\uff1f<\/strong><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-tabs-child uagb-tabs__body-container uagb-inner-tab-1\" aria-labelledby=\"uagb-tabs__tab1\">\n<p class=\"wp-block-paragraph\">Parkinson&#8217;s disease (PD) and glaucoma appear to be two distinct diseases\u2014one affecting motor control in the brain, the other causing vision loss\u2014but medical research has revealed a deep neurodegenerative link between them.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Simply put, they are like &#8220;relatives living in different organs,&#8221; sharing certain pathogenic biological blueprints.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">1. Shared Neurodegenerative Nature<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Parkinson&#8217;s disease primarily involves the loss of dopamine neurons in the brain, while glaucoma is caused by the apoptosis of retinal ganglion cells (RGCs) in the retina.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mechanisms of Apoptosis:<\/strong> Both involve mitochondrial dysfunction, oxidative stress, and inflammatory responses.<\/li>\n\n\n\n<li><strong>Protein Abnormalities:<\/strong> Studies have found abnormal protein deposits (such as \u03b2-synuclein) associated with Parkinson&#8217;s disease in the retinas of some glaucoma patients.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">2. The Key Role of Dopamine<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">We often think of dopamine only as being related to pleasure or movement in the brain, but <strong>dopamine neurons are also present in the retina<\/strong>.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Visual Accommodation:<\/strong> Dopamine in the retina is responsible for regulating contrast sensitivity, color perception, and light adaptation.<\/li>\n\n\n\n<li><strong>Interactions:<\/strong> Parkinson&#8217;s disease patients often experience retinal thinning due to a systemic decrease in dopamine levels. This thinning is very similar to the nerve damage caused by glaucoma in clinical imaging, sometimes leading to misdiagnosis or missed diagnosis.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">3. Potential Risks of Medication Use (Very Important)<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">If you or a loved one has both Parkinson&#8217;s disease and glaucoma, you must pay special attention to the effects of Parkinson&#8217;s medications on intraocular pressure:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Anticholinergics:<\/strong> Commonly used to treat tremor in Parkinson&#8217;s disease. These medications may cause mydriasis, potentially triggering <strong>acute occlusive glaucoma<\/strong>.<\/li>\n\n\n\n<li><strong>Levodopa (L-Dopa):<\/strong> While it&#8217;s the first-line treatment for Parkinson&#8217;s disease (PD), it may be associated with intraocular pressure fluctuations in rare cases.<\/li>\n<\/ul>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>\u26a0\ufe0f Important Reminder:<\/strong> If you are taking Parkinson&#8217;s medication and have been diagnosed with narrow-angle glaucoma, please inform your neurologist and ophthalmologist so that your medication can be adjusted.<\/p>\n<\/blockquote>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">4. Clinical Correlation Data<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">According to recent large-scale data tracking studies:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Parkinson&#8217;s patients generally have a slightly higher chance of developing glaucoma than their peers.<\/li>\n\n\n\n<li>Similarly, some glaucoma patients have a slightly increased risk of developing motor impairments or PD in the future.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This suggests that these two conditions may share a common genetic susceptibility.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">How Can I Help You?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The relationship between these two is very delicate. If you are asking on behalf of an elder, or if you yourself have related concerns, <strong>would you like to know the specific &#8220;medication safety checklist,&#8221; or want to know how Parkinson&#8217;s disease patients should perform daily eye care?<\/strong><\/p>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>The relationship between Parkinson&#8217;s disease and  [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-100","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/lovejade.org\/?author=1"},"uagb_comment_info":0,"uagb_excerpt":"The relationship between Parkinson&#8217;s disease and ...","_links":{"self":[{"href":"https:\/\/lovejade.org\/index.php?rest_route=\/wp\/v2\/posts\/100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lovejade.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lovejade.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lovejade.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lovejade.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=100"}],"version-history":[{"count":1,"href":"https:\/\/lovejade.org\/index.php?rest_route=\/wp\/v2\/posts\/100\/revisions"}],"predecessor-version":[{"id":101,"href":"https:\/\/lovejade.org\/index.php?rest_route=\/wp\/v2\/posts\/100\/revisions\/101"}],"wp:attachment":[{"href":"https:\/\/lovejade.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=100"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lovejade.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=100"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lovejade.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}